2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Cannabinoid Receptor

Cannabinoid Receptor

Cannabinoid Receptor

Cannabinoid Receptor

Related Products

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Cannabinoid receptors are currently classified into three groups: central (CB1), peripheral (CB2) and GPR55, all of which are G-protein-coupled. CB1 receptors are primarily located at central and peripheral nerve terminals. CB2 receptors are predominantly expressed in non-neuronal tissues, particularly immune cells, where they modulate cytokine release and cell migration. Recent reports have suggested that CB2 receptors may also be expressed in the CNS. GPR55 receptors are non-CB1/CB2 receptors that exhibit affinity for endogenous, plant and synthetic cannabinoids. Endogenous ligands for cannabinoid receptors have been discovered, including anandamide and 2-arachidonylglycerol.

Cannabinoid Receptor Isoform Specific Products:

Cannabinoid Receptor Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-116661
    Cannabigerovarin
    Cannabigerovarin (CRM) (Item No. 29117) is a certified reference material categorized as a phytocannabinoid.1 This product is intended for research and forensic applications.
    Cannabigerovarin
  • HY-129821
    PTI-1
    PTI-1 is a synthetic cannabinoid (CB) that contains the 1-pentyl-indole structure.
    PTI-1
  • HY-170476
    Δ8-THCB
    		Ligand
    Δ8-THCB (∆8-Tetrahydrocannabutol) is a structural analog of phytocannabinoids. Δ8-THCB is also an analog of Δ8-tetrahydrocannabinol.
    Δ8-THCB
  • HY-137543
    Δ8-Tetrahydrocannabivarin
    Δ8-Tetrahydrocannabivarin is a cannabinoid.
    Δ8-Tetrahydrocannabivarin
  • HY-170047A
    11-Nor-9(S)-carboxy-hexahydrocannabinol
    11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9α-carboxy-HHC) is structurally similar to known phytocannabinoids.
    11-Nor-9(S)-carboxy-hexahydrocannabinol
  • HY-15443R
    AM251 (Standard)
    		Antagonist
    AM251 (Standard) is the analytical standard of AM251. This product is intended for research and analytical applications. AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC50 of 39 nM.
    AM251 (Standard)
  • HY-165082
    Tricosanoyl ethanolamide
    		Activator
    Tricosanoyl ethanolamide is a member of endocannabinoids and its structure consists of ethanolamine and tricosanoic acid, which contains 23 carbon atoms. Tricosanoyl ethanolamide can be used for research of diseases related to the endocannabinoid system.
    Tricosanoyl ethanolamide
  • HY-170727
    Cannabinol acetate
    Cannabinol acetate (Acetylcannabinol) is structurally similar to known phytocannabinoids.
    Cannabinol acetate
  • HY-171024
    Cannabinol ethyl
    Cannabinol ethyl (CBN-C2) is structurally similar to known phytocannabinoids.
    Cannabinol ethyl
  • HY-168790
    8(S)-Hydroxy-9(S)-hexahydrocannabinol
    8(S)-Hydroxy-9(S)-hexahydrocannabinol is structurally similar to known phytocannabinoids.
    8(S)-Hydroxy-9(S)-hexahydrocannabinol
  • HY-170695
    exo-THCP
    exo-THCP (exo-Tetrahydrocannabiphorol) is structurally similar to known phytocannabinoids.
    exo-THCP
  • HY-W008364R
    Olivetol (Standard)
    		Inhibitor
    Olivetol (Standard) is the analytical standard of Olivetol. This product is intended for research and analytical applications. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively.
    Olivetol (Standard)
  • HY-170041
    (±)-6',7'-Dihydroxy cannabichromene
    (±)-6',7'-Dihydroxy cannabichromene is a phytocannabinoid metabolite.
    (±)-6',7'-Dihydroxy cannabichromene
  • HY-W195039
    5-Heptylresorcinol
    5-Heptylresorcinol is a precursor in the synthesis of cannabidiphorol.
    5-Heptylresorcinol
  • HY-150348
    Cannabidivarin diacetate
    Cannabidivarin diacetateis structurally similar to known phytocannabinoids.
    Cannabidivarin diacetate
  • HY-170739
    Δ9-THCBA-A
    Δ9-THCBA-A (Δ9-Tetrahydrocannabinolic acid-C4) is structurally similar to known phytocannabinoids.
    Δ9-THCBA-A
  • HY-170042
    5'-Hydroxy-9(S)-hexahydrocannabinol
    5'-Hydroxy-9(S)-hexahydrocannabinol is structurally similar to known phytocannabinoids.
    5'-Hydroxy-9(S)-hexahydrocannabinol
  • HY-121830
    5Z,8Z,11Z,14Z-Eicosatetraenoic acid, 3-thienylmethyl ester
    5Z,8Z,11Z,14Z-Eicosatetraenoic acid, 3-thienylmethyl ester is a Anandamide (HY-10863) analog. Anandamide is an endocannabinoid.
    5Z,8Z,11Z,14Z-Eicosatetraenoic acid, 3-thienylmethyl ester
  • HY-172082
    MEP-FUBICA
    MEP-FUBICA is structurally categorized as a synthetic cannabinoid.
    MEP-FUBICA
  • HY-W714389
    Cannabifuran
    Cannabifuran is structurally similar to known phytocannabinoids.
    Cannabifuran
Cat. No. Product Name / Synonyms Application Reactivity
Cannabinoid Receptor Isoform Comparison

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